(4-Cyano-2-methoxyphenyl)boronic acid

(4-Cyano-2-methoxyphenyl)boronic acid - Names and Identifiers

Name	(4-Cyano-2-methoxyphenyl)boronic acid
Synonyms	4-Cyano-2-methoxyphenylboronic acid (4-Cyano-2-methoxyphenyl)boronic acid Boronic acid, B-(4-cyano-2-methoxyphenyl)-
CAS	1256345-67-1
InChI	InChI=1S/C8H8BNO3/c1-13-8-4-6(5-10)2-3-7(8)9(11)12/h2-4,11-12H,1H3

(4-Cyano-2-methoxyphenyl)boronic acid - Physico-chemical Properties

Molecular Formula	C8H8BNO3
Molar Mass	176.96
Density	1.3±0.1 g/cm3
Boling Point	387.0±52.0 °C at 760 mmHg
Flash Point	187.8±30.7 °C
Vapor Presure	0.0±0.9 mmHg at 25°C
Appearance	Solid
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.547

(4-Cyano-2-methoxyphenyl)boronic acid - Introduction

4-Cyano-2-methoxyphenylboronic acid (phenyl acid) is an organic boron compound with the chemical formula C9H9BO3.

Nature:
-Appearance: White crystalline powder.
-Solubility: Soluble in many organic solvents such as dimethyl sulfoxide and methanol.
-Melting point: about 160-165°C.
-Mass: The molecular weight is 183.98g/mol.

Use:
-4-Cyano-2-methoxyphenylboronic acid can be used as a reagent in organic synthesis, especially as a ligand in Suzuki coupling reactions.
-In pharmaceutical research, it can also be used as a synthetic intermediate for active compounds.

Method:
-Generally, 4-cyano-2-methoxyphenyl boronic acid is prepared by a method of substituting phenyl boronic acid. This process requires a series of chemical reactions to introduce cyano and methoxy groups.

Safety Information:
-4-Cyano-2-methoxyphenylboronic acid is less toxic, but laboratory safety procedures should still be followed.
-During handling and storage, avoid inhalation and skin contact, and avoid contact with strong oxidants.
-If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 02:00:41